BDBM50106505 6-Chloro-7-(indan-1-ylamino)-quinoline-5,8-dione::CHEMBL131199

SMILES ClC1=C(NC2CCc3ccccc23)C(=O)c2ncccc2C1=O

InChI Key InChIKey=QNVSFGNOGHOYKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106505   

TargetM-phase inducer phosphatase 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106505(6-Chloro-7-(indan-1-ylamino)-quinoline-5,8-dione |...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50106505(6-Chloro-7-(indan-1-ylamino)-quinoline-5,8-dione |...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human NSD2 (941 to 1240 residues) using SAM as substrate incubated for 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed