BDBM50106365 CHEMBL3596492

SMILES CN1CCC(COCc2cc(cc(c2)C(F)(F)F)-c2ccc(cc2)C#N)(CC1)c1ccccc1

InChI Key InChIKey=AGAVJQRYUXAJGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106365   

TargetSubstance-P receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50106365(CHEMBL3596492)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50106365(CHEMBL3596492)
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]-substance P from gerbil NK1 receptor expressed in HEK293 cell membranes incubated for 30 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed