BDBM50106196 (1H )-Quinazolin-2,4-dione::1H-Quinazoline-2,4-dione (Benzoylenurea)::CHEMBL421646::Quinazoline-2,4-diol

SMILES c1ccc2c(c1)C(=O)NC(=O)N2

InChI Key InChIKey=SDQJTWBNWQABLE-UHFFFAOYSA-N

Data  4 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50106196   

TargetPoly [ADP-ribose] polymerase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50106196((1H )-Quinazolin-2,4-dione | Quinazoline-2,4-diol ...)
Affinity DataIC50: 8.10E+3nMAssay Description:The compound was tested for poly(ADP-ribose)-polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50106196((1H )-Quinazolin-2,4-dione | Quinazoline-2,4-diol ...)
Affinity DataKi:  8.65E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase-12 preincubated for 6 hrs by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50106196((1H )-Quinazolin-2,4-dione | Quinazoline-2,4-diol ...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase-9 preincubated for 6 hrs by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50106196((1H )-Quinazolin-2,4-dione | Quinazoline-2,4-diol ...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human recombinant carbonic anhydrase-1 preincubated for 6 hrs by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50106196((1H )-Quinazolin-2,4-dione | Quinazoline-2,4-diol ...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 preincubated for 6 hrs by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2018
Entry Details Article
PubMed