BDBM50106144 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(4-phenyl-piperazin-1-ylmethyl)-benzamide::CHEMBL319902

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(CC2)c2ccccc2)cc(Br)cc1C(=O)NO

InChI Key InChIKey=JIYWMQDJGOAJMD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106144   

LigandPNGBDBM50106144(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 87nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106144(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106144(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 444nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106144(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed