BDBM50106141 4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-5-(4-methyl-piperazin-1-ylmethyl)-4'-trifluoromethoxy-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL102057

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(C)CC2)cc(cc1C(=O)NO)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=CLPQPSHMBDAYLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106141   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106141(4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-5-(4-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106141(4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-5-(4-...)
Affinity DataIC50: 745nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106141(4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-5-(4-...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50106141(4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-5-(4-...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed