BDBM50106140 4-{5-Bromo-3-hydroxycarbamoyl-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-benzyl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL101210

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(CC2)C(=O)OC(C)(C)C)cc(Br)cc1C(=O)NO

InChI Key InChIKey=FMQWWPFJFLUCHZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106140   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106140(4-{5-Bromo-3-hydroxycarbamoyl-2-[(4-methoxy-benzen...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106140(4-{5-Bromo-3-hydroxycarbamoyl-2-[(4-methoxy-benzen...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50106140(4-{5-Bromo-3-hydroxycarbamoyl-2-[(4-methoxy-benzen...)
Affinity DataIC50: 63nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106140(4-{5-Bromo-3-hydroxycarbamoyl-2-[(4-methoxy-benzen...)
Affinity DataIC50: 674nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed