BDBM50106133 5-Bromo-2-{[4-(4-chloro-phenoxy)-benzenesulfonyl]-methyl-amino}-N-hydroxy-3-(4-methyl-piperazin-1-ylmethyl)-benzamide::CHEMBL101612

SMILES CN(c1c(CN2CCN(C)CC2)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key InChIKey=LGVIBWRSRHZDQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106133   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106133(5-Bromo-2-{[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106133(5-Bromo-2-{[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50106133(5-Bromo-2-{[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of TNFalpha converting enzyme, TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106133(5-Bromo-2-{[4-(4-chloro-phenoxy)-benzenesulfonyl]-...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed