BDBM50106129 5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(4-methyl-piperazin-1-yl)-but-2-ynyl]-amino}-3-methyl-benzamide::CHEMBL319887

SMILES COc1ccc(cc1)S(=O)(=O)N(CC#CCN1CCN(C)CC1)c1c(C)cc(Br)cc1C(=O)NO

InChI Key InChIKey=HEYGZWVOCCBCPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106129   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106129(5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106129(5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 129nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106129(5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50106129(5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed