BDBM50106128 CHEMBL100081::N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-amino}-3-methyl-benzamide

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(OCCN2CCCCC2)cc1)c1c(C)cccc1C(=O)NO

InChI Key InChIKey=QDBZCMIHMMMYES-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106128   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106128(N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-pip...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106128(N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-pip...)
Affinity DataIC50: 176nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50106128(N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-pip...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50106128(N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-pip...)
Affinity DataIC50: 277nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed