BDBM50106064 (S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL98858

SMILES NC(=N)c1cccc(c1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=GFNNYWHGGRIURL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106064   

TargetVitamin K-dependent protein C(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106064((S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106064((S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 7.79E+4nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106064((S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106064((S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106064((S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of human coagulation factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50106064((S)-2-(3-Carbamimidoyl-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 2.15E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed