BDBM50106012 CHEMBL3598078

SMILES CC(C)n1nc(NC(C)=O)nc1-c1cnc(N(C)C(=O)c2c(F)cccc2Cl)c(c1)N1CCCCC1

InChI Key InChIKey=XHFVNNYFDCLKOC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106012   

TargetNuclear receptor ROR-gamma(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50106012(CHEMBL3598078)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to GST-tagged RORgamma LBD (unknown origin) assessed as inhibition of interaction with co-activatior peptide TRAP220 preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50106012(CHEMBL3598078)
Affinity DataEC50: >1.00E+3nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) transfected in HEK293T cells after 16 to 20 hrs by GAL4 luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed