BDBM50105726 CHEMBL318924::Dipropyl-(R)-5,6,7,8-tetrahydro-indolizin-7-yl-amine

SMILES CCCN(CCC)[C@@H]1CCn2cccc2C1

InChI Key InChIKey=BCXCDTKLXHURCX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105726   

TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50105726(Dipropyl-(R)-5,6,7,8-tetrahydro-indolizin-7-yl-ami...)
Affinity DataKi:  150nMAssay Description:In vitro ability to displace [3H]pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50105726(Dipropyl-(R)-5,6,7,8-tetrahydro-indolizin-7-yl-ami...)
Affinity DataKi:  560nMAssay Description:In vitro ability to displace [3H]spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50105726(Dipropyl-(R)-5,6,7,8-tetrahydro-indolizin-7-yl-ami...)
Affinity DataKi:  4.10E+3nMAssay Description:In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50105726(Dipropyl-(R)-5,6,7,8-tetrahydro-indolizin-7-yl-ami...)
Affinity DataKi: >1.00E+5nMAssay Description:In vitro ability to displace [3H]SCH-23390 from bovine cloned Dopamine receptor D1 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed