BDBM50105692 (E)-3-[4-(4-tert-Butyl-benzenesulfonylamino)-phenyl]-N-hydroxy-acrylamide::3-(4-(4-tert-butylphenylsulfonamido)phenyl)-N-hydroxyacrylamide::3-[4-(4-tert-Butyl-benzenesulfonylamino)-phenyl]-N-hydroxy-acrylamide::CHEMBL97272::US8796330, 105

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=XXQMHYGLGPUUDQ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105692   

TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50105692(US8796330, 105 | (E)-3-[4-(4-tert-Butyl-benzenesul...)
Affinity DataIC50: 200nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50105692(US8796330, 105 | (E)-3-[4-(4-tert-Butyl-benzenesul...)
Affinity DataIC50: 100nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50105692(US8796330, 105 | (E)-3-[4-(4-tert-Butyl-benzenesul...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

US Patent
LigandPNGBDBM50105692(US8796330, 105 | (E)-3-[4-(4-tert-Butyl-benzenesul...)
Affinity DataEC50:  5.00E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed