BDBM50105608 5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrazol-3-yl)-ureido]-thiophene-2-carboxylic acid methyl ester::CHEMBL95114::methyl 5-tert-butyl-3-(3-(1-isopropyl-1H-pyrazol-3-yl)ureido)thiophene-2-carboxylate

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccn(n1)C(C)C)C(C)(C)C

InChI Key InChIKey=XTLXHNCAFBMIOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50105608   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105608(methyl 5-tert-butyl-3-(3-(1-isopropyl-1H-pyrazol-3...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Raf-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105608(methyl 5-tert-butyl-3-(3-(1-isopropyl-1H-pyrazol-3...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed