BDBM50105543 Allyl-{1-[(3S,4S)-1-(2-chloro-benzoyl)-4-phenyl-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester::Allyl-{1-[1-(2-chloro-benzoyl)-4-phenyl-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester::CHEMBL328297

SMILES [O-][N+](=O)c1ccc(COC(=O)N(CC=C)C2CCN(C[C@H]3CN(C[C@@H]3c3ccccc3)C(=O)c3ccccc3Cl)CC2)cc1

InChI Key InChIKey=HMSHDJLBXUWAQR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105543   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105543(Allyl-{1-[1-(2-chloro-benzoyl)-4-phenyl-pyrrolidin...)
Affinity DataIC50: 0.800nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105543(Allyl-{1-[1-(2-chloro-benzoyl)-4-phenyl-pyrrolidin...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105543(Allyl-{1-[1-(2-chloro-benzoyl)-4-phenyl-pyrrolidin...)
Affinity DataIC50: 0.800nMAssay Description:Displacement inhibition of 125-I labeled MIP-alpha from CCR5 receptor expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed