BDBM50105531 1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)1-oxide]::1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophenium-3,4'-(hexahydropyridine)]-1-olate::CHEMBL330528

SMILES O=S1CC2(CCN(C[C@H]3CN(C[C@@H]3c3ccccc3)S(=O)(=O)c3ccccc3)CC2)c2ccccc12

InChI Key InChIKey=IUMHTNIGQVOIEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105531   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105531(1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1...)
Affinity DataIC50: 26nMAssay Description:Ability to displace [125 I]-MIP-1alpha from C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105531(1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105531(1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1...)
Affinity DataIC50: 26nMAssay Description:Ability to displace [125 I]-MIP-1alpha from C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed