BDBM50105453 2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-2-methyl-3-(4-phenoxy-benzenesulfonyl)-propionamide::CHEMBL92923

SMILES CC(CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)(NCc1ccc2OCOc2c1)C(=O)NO

InChI Key InChIKey=DSBXKNRWNDALKK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105453   

Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 0.500nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed