BDBM50105450 2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL92899

SMILES ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccccc3)cc2)CCCN1CC#C

InChI Key InChIKey=BHBGOKVZFAQJAD-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50105450   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed