BDBM50105304 CHEMBL3597781

SMILES Clc1ccc(Br)cc1[C@@H]1C[C@@H](Nc2nnnn12)c1cccc(Br)c1

InChI Key InChIKey=FFJYBALXSFFKRZ-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105304   

TargetEndothelial PAS domain-containing protein 1(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50105304(CHEMBL3597781)
Affinity DataKd: >2.00E+3nMAssay Description:Binding affinity to wild type His6-Gbeta1-fused HIF-2alpha PAS-B domain (240 to 350) (unknown origin) expressed in Escherichia coli by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetEndothelial PAS domain-containing protein 1(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50105304(CHEMBL3597781)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50105304(CHEMBL3597781)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to wild type GST-tagged HIF-2alpha PAS-B S304M mutant (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed