BDBM50105175 4-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-1,1-difluoro-ethyl}-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid methylamide::CHEMBL115431

SMILES CCOCCOCCOCC(F)(F)c1ccc(Oc2cncc3sc(cc23)C(=O)NC)cc1

InChI Key InChIKey=JMJICFDZSPGFFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105175   

TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105175(4-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-1,1-difluoro-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105175(4-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-1,1-difluoro-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105175(4-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-1,1-difluoro-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed