BDBM50105034 4-tert-Butyl-N-{6-[2-(5-methoxy-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-benzenesulfonamide::CHEMBL113757

SMILES COc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)c2-c2ccc(C)cc2)nc1

InChI Key InChIKey=AFDNMXWXTQCYFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105034   

TargetEndothelin-1 receptor(Pig)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105034(4-tert-Butyl-N-{6-[2-(5-methoxy-pyrimidin-2-yloxy)...)
Affinity DataIC50: 0.00170nMAssay Description:In vitro inhibition of [125I]ET1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed