BDBM50104980 11-(2'-Methanesulfonyl-biphenyl-4-ylmethyl)-2,10-dioxo-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide]::CHEMBL324549

SMILES CS(=O)(=O)c1ccccc1-c1ccc(C[C@@H]2[C@H](CCCOC(=O)NCCCC[C@H](NC2=O)C(=O)NCC(=O)N2CCOCC2)C(=O)NO)cc1

InChI Key InChIKey=KNGLZBYFVBOFMQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104980   

LigandPNGBDBM50104980(11-(2'-Methanesulfonyl-biphenyl-4-ylmethyl)-2,10-d...)
Affinity DataKi:  6.5nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104980(11-(2'-Methanesulfonyl-biphenyl-4-ylmethyl)-2,10-d...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104980(11-(2'-Methanesulfonyl-biphenyl-4-ylmethyl)-2,10-d...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104980(11-(2'-Methanesulfonyl-biphenyl-4-ylmethyl)-2,10-d...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed