BDBM50104926 CHEMBL3597636

SMILES OC(CCNC(=O)c1cnc2ccccc2c1)CN1CCN(CC1)c1cccc2ccccc12

InChI Key InChIKey=KRUWNGHFXJBYSG-UHFFFAOYSA-N

Data  5 KI  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50104926   

Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataEC50:  17nMAssay Description:Agonist activity at 5HT1A receptor (unknown origin) by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as stimulation of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataIC50: 720nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataKi:  44nMAssay Description:Displacement of [125I]DOI from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50104926(CHEMBL3597636)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed