BDBM50104518 3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2-yl]-meth-(Z)-ylidene]-6-[1-phenyl-meth-(Z)-ylidene]-piperazine-2,5-dione; hydrochloride::CHEMBL40180::CHEMBL544314

SMILES CN(C)CCSc1ccc(\C=c2/[nH]c(=O)\c(=C\c3ccccc3)[nH]c2=O)s1

InChI Key InChIKey=ODQGWMYUSNRXFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50104518   

TargetPlasminogen activator inhibitor 1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50104518(CHEMBL544314 | CHEMBL40180 | 3-[1-[5-(2-Dimethylam...)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibitory activity against plasminogen activator inhibitor 1 (PAI-1) was evaluated by inhibition of tissue plasminogen activator/PAI-1 complex forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50104518(CHEMBL544314 | CHEMBL40180 | 3-[1-[5-(2-Dimethylam...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50104518(CHEMBL544314 | CHEMBL40180 | 3-[1-[5-(2-Dimethylam...)
Affinity DataIC50: 3.50E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed