BDBM50104287 CHEMBL3594136

SMILES CC(C)c1ccc(cc1)C1NC(=O)c2ccccc2N1

InChI Key InChIKey=NYTCUHJCCYJJIL-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50104287   

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full-length human ARTD3 using 500 nM NAD substrate after 1 hrs incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ARTD7 (460 to 656) using 250 nM NAD substrate at 10 uM after 2 hrs incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ARTD10 (809 to 1017) using 500 nM NAD substrate at 10 uM after 2.5 hrs incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full-length human ARTD2 using 500 nM NAD substrate after 3 hrs incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full-length human ARTD1 using 500 nM NAD substrate after 1 hr incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human TNKS1 (1030 to 1317) using NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 230nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50104287(CHEMBL3594136)
Affinity DataIC50: 234nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed