BDBM50104235 CHEMBL85086::{1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-ethyl-carbamic acid benzyl ester

SMILES CCN(C1CCN(CC[C@H](CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1)C(=O)OCc1ccccc1

InChI Key InChIKey=ZXGGAWLLOZVQTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104235   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104235({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104235({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104235({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 5 in CHO cells with [125I]-MIP-1 alpha radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104235({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at Homo sapiens (human) CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article