BDBM50104228 CHEMBL79369::N-[(S)-2-(3-Chloro-phenyl)-4-(4-o-tolyl-piperazin-1-yl)-butyl]-N-methyl-benzenesulfonamide

SMILES CN(C[C@@H](CCN1CCN(CC1)c1ccccc1C)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=ASNNTFFABYDNRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104228   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104228(N-[(S)-2-(3-Chloro-phenyl)-4-(4-o-tolyl-piperazin-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104228(N-[(S)-2-(3-Chloro-phenyl)-4-(4-o-tolyl-piperazin-...)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at Homo sapiens (human) CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article