BDBM50104122 9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL301242
SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3cccc4C(=O)c5ccccc5-c34)CC2)c1Cl
InChI Key InChIKey=WOWYFQWPMWYJNL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50104122
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity at dopamine receptor D3 on Sf9 cells by [125I]IABN displacement.More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity at dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards rat Dopamine receptor D3 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]IABN as radioligandMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 19.4nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 70.1nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D2L receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity at dopamine receptor D2 on Sf9 cells by [125I]IABN displacement.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Binding affinity at human dopamine receptor D2More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Inhibition of [3H]YM-09151-2 binding to primate Dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Binding affinity towards rat Dopamine receptor D2 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]IABN as radioligandMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.12E+3nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D4 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.85E+3nMAssay Description:Binding affinity at human dopamine receptor D4More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.85E+3nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair