BDBM50104010 1-(4-Methoxy-benzenesulfonyl)-3-(4-methoxy-benzylsulfanylmethyl)-4,4-dimethyl-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL323575

SMILES COc1ccc(CSCC2[C@@H](N(CC2(C)C)S(=O)(=O)c2ccc(OC)cc2)C(=O)NO)cc1

InChI Key InChIKey=WNQMYJZKTYVQPU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50104010   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104010(1-(4-Methoxy-benzenesulfonyl)-3-(4-methoxy-benzyls...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104010(1-(4-Methoxy-benzenesulfonyl)-3-(4-methoxy-benzyls...)
Affinity DataIC50: 17nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104010(1-(4-Methoxy-benzenesulfonyl)-3-(4-methoxy-benzyls...)
Affinity DataIC50: 22nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104010(1-(4-Methoxy-benzenesulfonyl)-3-(4-methoxy-benzyls...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104010(1-(4-Methoxy-benzenesulfonyl)-3-(4-methoxy-benzyls...)
Affinity DataIC50: 458nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed