BDBM50104009 3-Benzyloxymethyl-1-(4-methoxy-benzenesulfonyl)-4,4-dimethyl-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL322412

SMILES COc1ccc(cc1)S(=O)(=O)N1CC(C)(C)C(COCc2ccccc2)[C@@H]1C(=O)NO

InChI Key InChIKey=ZAVWWISQYKVWCT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50104009   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104009(3-Benzyloxymethyl-1-(4-methoxy-benzenesulfonyl)-4,...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104009(3-Benzyloxymethyl-1-(4-methoxy-benzenesulfonyl)-4,...)
Affinity DataIC50: 32nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104009(3-Benzyloxymethyl-1-(4-methoxy-benzenesulfonyl)-4,...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104009(3-Benzyloxymethyl-1-(4-methoxy-benzenesulfonyl)-4,...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50104009(3-Benzyloxymethyl-1-(4-methoxy-benzenesulfonyl)-4,...)
Affinity DataIC50: 44nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed