BDBM50103890 CHEMBL532818

SMILES COc1cccc2c(NCCNc3ccnc4c(OC)cccc34)ccnc12

InChI Key InChIKey=OBEXOFONJDJASX-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50103890   

TargetAlpha-1A adrenergic receptor(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]-prazosin from human alpha1A adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  195nMAssay Description:Binding affinity to human alpha1A adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  324nMAssay Description:Binding affinity to human alpha1B adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  324nMAssay Description:Displacement of [3H]-prazosin from human alpha1B adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]-prazosin from human alpha1D adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to human alpha1D adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  3.09E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Unsw Australia

Curated by ChEMBL
LigandPNGBDBM50103890(CHEMBL532818)
Affinity DataKi:  3.09E+3nMAssay Description:Binding affinity to human 5HT1A receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed