BDBM50103821 CHEMBL310038::[2-(3-Hydroxy-4-methoxy-phenyl)-6-methoxy-benzo[b]thiophen-3-yl]-(3,4,5-trimethoxy-phenyl)-methanone

SMILES COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c(sc2c1)-c1ccc(OC)c(O)c1

InChI Key InChIKey=GGRHSLQJYQUKGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103821   

TargetTubulin alpha-1A chain(Pig)
Australian National University

Curated by ChEMBL
LigandPNGBDBM50103821([2-(3-Hydroxy-4-methoxy-phenyl)-6-methoxy-benzo[b]...)
Affinity DataIC50: 3.40E+3nMAssay Description:Compound was evaluated for inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Australian National University

Curated by ChEMBL
LigandPNGBDBM50103821([2-(3-Hydroxy-4-methoxy-phenyl)-6-methoxy-benzo[b]...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of tubulin (10 uM) polymerization, after a 20 min incubation at 30 degrees CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed