BDBM50103430 6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carbonyl]-amino}-butyrylamino)-hexanoic acid tert-butyl ester::CHEMBL99895

SMILES C[C@@H](c1c[nH]c2c1cccc2)[C@H](C(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C)NC(=O)N3CCC(CC3)N4c5ccccc5NC4=O

InChI Key InChIKey=WFCIXKAZBUIFTR-UHFFFAOYSA-N

Data  11 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50103430   

TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing each of the cloned human SRIF receptor (sst-2) subtypesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity towards Somatostatin receptor type 2 (hsst2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to human somatostatin receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  31nMAssay Description:Binding affinity towards Somatostatin receptor type 3 (hsst3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human somatostatin receptor type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSomatostatin receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  81nMAssay Description:Binding affinity towards Somatostatin receptor type 4 (hsst4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  81nMAssay Description:Binding affinity to human somatostatin receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  163nMAssay Description:Binding affinity towards Somatostatin receptor type 5 (hsst5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  163nMAssay Description:Binding affinity to human somatostatin receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSomatostatin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  2.39E+3nMAssay Description:Binding affinity towards Somatostatin receptor type 1 (hsst1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  2.39E+3nMAssay Description:Binding affinity to human somatostatin receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed