BDBM50103413 CHEMBL3398227

SMILES OC(=O)COc1cccc2CC(Cn3ncc(-c4ccccc4F)c(-c4ccccc4)c3=O)CCc12

InChI Key InChIKey=INNXTRNVCBZPHW-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103413   

TargetProstaglandin D2 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103413(CHEMBL3398227)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human recombinant DP1 receptor expressed in melanophores assessed as induction of pigment redistribution incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103413(CHEMBL3398227)
Affinity DataIC50: 220nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103413(CHEMBL3398227)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetProstacyclin receptor(Rat)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103413(CHEMBL3398227)
Affinity DataEC50:  420nMAssay Description:Agonist activity at rat recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed