BDBM50103392 CHEMBL3398232

SMILES OC(=O)COc1cccc2CC(Cn3ncc(-c4ccccc4)c(-c4ccc(F)cc4)c3=O)CCc12

InChI Key InChIKey=XLPXKHYJSLBZBT-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103392   

TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103392(CHEMBL3398232)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103392(CHEMBL3398232)
Affinity DataIC50: 230nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetProstacyclin receptor(Rat)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103392(CHEMBL3398232)
Affinity DataEC50:  170nMAssay Description:Agonist activity at rat recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed