BDBM50103314 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2,3-dimethyl-2,3-dihydro-isoxazole::CHEMBL322240

SMILES CC1N(C)OC(=C1c1ccc(F)cc1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=CARDZWUJKAFXIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103314   

TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50103314(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50103314(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50103314(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 32nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed