BDBM50103191 CHEMBL3393199

SMILES COc1cc2nncc(-c3cnc(N4CCC(O)(CC4)c4cccnc4)c(Cl)c3)c2cc1OC

InChI Key InChIKey=OVMSZRUWEZLQRM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103191   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University

Curated by ChEMBL

LigandBDBM50103191(CHEMBL3393199)Copy SMILESCopy InChI

Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain pre-incubated for 5 mins before [3H]cAMP substrate addition and measured 20 mins post substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2016
Entry Details Article
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