BDBM50103168 CHEMBL71686::N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl-benzenesulfonyl)-amino]-benzamide

SMILES CN(c1c(C)cc(C)cc1C(=O)NO)S(=O)(=O)c1ccc(Sc2ccccc2)cc1

InChI Key InChIKey=RRSNDPJAXNKWJB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103168   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl...)
Affinity DataIC50: 8nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50103168(N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl...)
Affinity DataIC50: 727nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl...)
Affinity DataIC50: 1.31E+3nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed