BDBM50103165 CHEMBL68212::N-Hydroxy-3-methyl-2-{methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-benzamide

SMILES CN(c1c(C)cccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1

InChI Key InChIKey=QYEGLTVXUKXPSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103165   

TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103165(N-Hydroxy-3-methyl-2-{methyl-[4-(pyridin-4-yloxy)-...)
Affinity DataIC50: 3.25E+3nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103165(N-Hydroxy-3-methyl-2-{methyl-[4-(pyridin-4-yloxy)-...)
Affinity DataIC50: 7nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103165(N-Hydroxy-3-methyl-2-{methyl-[4-(pyridin-4-yloxy)-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed