BDBM50103163 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiazol-2-ylmethoxy)-biphenyl-4-sulfonyl]-amino}-benzamide::CHEMBL71227

SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2nccs2)cc1

InChI Key InChIKey=PYSVMZGECWVLOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103163   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103163(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiazol-...)
Affinity DataIC50: 661nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50103163(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiazol-...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103163(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiazol-...)
Affinity DataIC50: 952nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed