BDBM50103161 3-Furan-2-yl-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-benzamide::CHEMBL69268

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccco1)C(=O)NO

InChI Key InChIKey=CBKKHHSQVZVIBM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103161   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103161(3-Furan-2-yl-N-hydroxy-2-[(4-methoxy-benzenesulfon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103161(3-Furan-2-yl-N-hydroxy-2-[(4-methoxy-benzenesulfon...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103161(3-Furan-2-yl-N-hydroxy-2-[(4-methoxy-benzenesulfon...)
Affinity DataIC50: 8nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50103161(3-Furan-2-yl-N-hydroxy-2-[(4-methoxy-benzenesulfon...)
Affinity DataIC50: 61nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed