BDBM50103160 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::CHEMBL71725

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(Br)cc1C(=O)NO

InChI Key InChIKey=CZYVJSTWDMVAFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103160   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103160(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 24nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50103160(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103160(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 20nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103160(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-p...)
Affinity DataIC50: 124nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed