BDBM50103157 2-[Benzyl-(4-phenethyloxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide::CHEMBL71007

SMILES Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OCCc3ccccc3)cc2)c(c1)C(=O)NO

InChI Key InChIKey=QVIMBPCQZGHONM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103157   

LigandPNGBDBM50103157(2-[Benzyl-(4-phenethyloxy-benzenesulfonyl)-amino]-...)
Affinity DataIC50: 467nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103157(2-[Benzyl-(4-phenethyloxy-benzenesulfonyl)-amino]-...)
Affinity DataIC50: 747nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103157(2-[Benzyl-(4-phenethyloxy-benzenesulfonyl)-amino]-...)
Affinity DataIC50: 75nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103157(2-[Benzyl-(4-phenethyloxy-benzenesulfonyl)-amino]-...)
Affinity DataIC50: 46nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed