BDBM50103153 2-[Benzyl-(4-ethoxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide::CHEMBL70957

SMILES CCOc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(C)cc(C)cc1C(=O)NO

InChI Key InChIKey=RGJXGQMBVWRXCQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103153   

LigandPNGBDBM50103153(2-[Benzyl-(4-ethoxy-benzenesulfonyl)-amino]-N-hydr...)
Affinity DataIC50: 173nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103153(2-[Benzyl-(4-ethoxy-benzenesulfonyl)-amino]-N-hydr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103153(2-[Benzyl-(4-ethoxy-benzenesulfonyl)-amino]-N-hydr...)
Affinity DataIC50: 291nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed