BDBM50103087 CHEMBL305026::[4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-3-methyl-piperazin-1-yl)-piperidin-1-yl]-(2,6-dimethyl-phenyl)-methanone

SMILES C[C@H](N1CCN(C[C@H]1C)C1CCN(CC1)C(=O)c1c(C)cccc1C)c1ccc(cc1)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=UUUTYZGDRKVSOB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103087   

TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103087([4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataIC50: 440nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103087([4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  0.800nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103087([4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against human muscarinic acetylcholine receptor M2 using [3H]N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed