BDBM50103059 CHEMBL302113::{(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-[2-(4-methoxy-phenyl)-5-(naphthalen-1-ylcarbamoylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester

SMILES COc1ccc(cc1)C1Sc2ccccc2N(CC(=O)Nc2cccc3ccccc23)C(=O)C1NC(=O)[C@H](Cc1ccc(OP(O)(=O)OCc2ccccc2)cc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=JQCKKEWSOORMRU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103059   

LigandPNGBDBM50103059({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 2.60E+4nMAssay Description:Binding affinity for Src protein tyrosine kinase SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103059({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 2.60E+4nMAssay Description:Binding affinity was determined on Src protein tyrosine kinase SH2 domain using fluorescence polarization assay with 2% DMSO in buffer solutionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103059({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Binding affinity was determined on Src protein tyrosine kinase SH2 domain using fluorescence polarization assay with 2% DMSO in buffer solutionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103059({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 1.33E+5nMAssay Description:Binding affinity was determined on Src protein tyrosine kinase SH2 domain using fluorescence polarization assay with 2% DMSO in buffer solutionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed