BDBM50103044 CHEMBL430262::{(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl]-1-[5-(3-cyclohexyl-propyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OP(O)(=O)OCc2ccccc2)cc1)C(=O)NC1CSc2ccccc2N(CCCC2CCCCC2)C1=O

InChI Key InChIKey=GYCWJRXLQZOBIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103044   

LigandPNGBDBM50103044({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 8.70E+4nMAssay Description:Binding affinity for Src protein tyrosine kinase SH2 domain using fluorescence polarization assay with 20% DMSO in buffer solutionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103044({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 2.60E+4nMAssay Description:Binding affinity was determined on Src protein tyrosine kinase SH2 domain using fluorescence polarization assay with 2% DMSO in buffer solutionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103044({(S)-2-[4-(Benzyloxy-hydroxy-phosphoryloxy)-phenyl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity for Src protein tyrosine kinase SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed