BDBM50102946 (3R,4S)-4-(4-Chloro-phenyl)-3-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-1-methyl-piperidine::CHEMBL265226

SMILES CC(C)c1noc(n1)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1

InChI Key InChIKey=QCRFJHAVUVDQDC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102946   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102946((3R,4S)-4-(4-Chloro-phenyl)-3-(3-isopropyl-[1,2,4]...)
Affinity DataKi:  391nMAssay Description:Displacement of [3H]WIN-35248 from dopamine transporter (DAT) of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102946((3R,4S)-4-(4-Chloro-phenyl)-3-(3-isopropyl-[1,2,4]...)
Affinity DataKi:  494nMAssay Description:Displacement of [3H]WIN-35248 from dopamine transporter (DAT) of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102946((3R,4S)-4-(4-Chloro-phenyl)-3-(3-isopropyl-[1,2,4]...)
Affinity DataKi:  778nMAssay Description:Evaluated for ability to inhibit high affinity uptake of [3H]-NE using rat nerve endings obtained from brain regions enriched in Norepinephrine trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102946((3R,4S)-4-(4-Chloro-phenyl)-3-(3-isopropyl-[1,2,4]...)
Affinity DataKi:  2.92E+3nMAssay Description:Displacement of [3H]5-HT from serotonin transporter of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed