BDBM50102944 (3R,4S)-3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-yl]-4-(4-chloro-phenyl)-1-methyl-piperidine::CHEMBL64007

SMILES CN1CC[C@@H]([C@H](C1)c1nc(no1)-c1ccc(Br)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=VGTHXWPAVSKNJJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102944   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102944((3R,4S)-3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-y...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]WIN-35248 from dopamine transporter (DAT) of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102944((3R,4S)-3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-y...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]5-HT from serotonin transporter of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102944((3R,4S)-3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-y...)
Affinity DataKi: >3.00E+3nMAssay Description:Evaluated for ability to inhibit high affinity uptake of [3H]-NE using rat nerve endings obtained from brain regions enriched in Norepinephrine trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50102944((3R,4S)-3-[3-(4-Bromo-phenyl)-[1,2,4]oxadiazol-5-y...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of high affinity uptake of [3H]DA using rat nerve endings obtained from brain regions enriched in DAT.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed