BDBM50102791 2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine::CHEMBL92251

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cc(Cl)cc(-c2ccccc2)c1O

InChI Key InChIKey=RUJOXQDERXMGDN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102791   

TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102791(2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimida...)
Affinity DataKi:  280nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen ActivatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102791(2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimida...)
Affinity DataKi:  500nMAssay Description:Inhibitory concentration against Human Serine Protease Urokinase Plasminogen ActivatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102791(2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimida...)
Affinity DataKi:  940nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102791(2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimida...)
Affinity DataKi:  3.30E+3nMAssay Description:Activity against Human Serine Protease TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102791(2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimida...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of Human Serine Protease PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102791(2-(5-Chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimida...)
Affinity DataKi:  1.20E+4nMAssay Description:Activity against Human Serine Protease ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed